Angelique (Tautou) is an art student in Bordeaux who’s madly in love with Loic (Le Bihan), a married cardiologist whose wife is about to have their first child. She confides to her friend Heloise (Guillemin) that Loic is planning to leave his wife, and pursues him with relentlessly sunny ardor, even when his personal life begins to fracture, and it becomes obvious there’s a more sinister layer to their relationship...

Tautou, the kewpie-doll-cute star of “Amelie,” is perfectly cast in Colombani’s clever black comedy as an abundantly talented young painter whose lover adores her. But does he? To say more would reveal too much of Colombani’s intelligent, perspective-shifting plot structure, which turns one person’s bliss into another’s nightmare. The ultimate anti-date movie, Colombani’s “He Loves Me” is an impish romance flick with a decidedly wicked French twist.